Changing sound driver is not an option because it says that there are none, but only with anything but wine ver. Changing wine version to the one recommended in the wine directory caused an error saying GTA IV needs a sound card to run.
It actually almost worked with update 3, but couldn't start the game or even change screen resolution.
Whole install works fine, then will not launch from the desktop shortcut or the /home/.wine/drive_c/program files(x86)/rockstar games/launchgtaiv.exe Now I cannot get it to boot, always crashes with the only error message being the playonlinux one. In my tests I installed the game and then applied the 1.0.7.0 patch. It works with every other game I have tried, including World of Tanks, Portal, Portal 2, Half-Life, BioShock, World of Warcraft, Garry's mod and more. I have tried playing GTA IV on PoL and Wine without luck.